发明名称 |
Mucin-immunoglobulin fusion proteins |
摘要 |
A fusion polypeptide comprising a) a mucin polypeptide having a glycan repertoire including the following sequence i) Hex-HexNol-HexN-Hex-Hex ii) NeuAc-Hex-HexNol-HexN- Hex-Hex and iii) NeuGc-Hex-HexNol-HexN-Hex-Hex; and b) at least a region of an immunoglobulin polypeptide wherein the fusion polypeptide binds a Gal-alpha, 3Gal specific antibody.
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申请公布号 |
NZ538629(A) |
申请公布日期 |
2008.05.30 |
申请号 |
NZ20030538629 |
申请日期 |
2003.08.11 |
申请人 |
RECOPHARMA AB |
发明人 |
HOLGERSSON, JAN;LIU, JINING;GUSTAFSSON, ANKI |
分类号 |
C12N15/09;A61K38/00;A61P37/06;C07K14/47;C07K16/00;C07K19/00;C12N1/19;C12N1/21;C12N5/10;C12N9/24;C12P21/02;(IPC1-7):C07K14/705 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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