COMPUESTOS AMINO-5-[-4-(DIFLOUROMETOXI) FENIL SUSTITUIDO]-5-FENILMIDAZOLONA, INHIBIDORES DE B-SECRETASA; COMPOSICION FARMACEUTICA QUE COMPRENDE A DICHOS COMPUESTOS; Y SU USO PARA TRATAR ALZHEIMER, DETERIORO COGNITIVO, SINDROME DE DOWN, DISMINUCION CO

摘要

The present invention provides a 2-amino-5-[substituted-4-(difluoromethoxy)phenyl]-5-phenylimidazolone compound of formula I The present invention also provides methods for the use thereof to inhibit beta-secretase (BACE) and treat beta-amyloid deposits and neurofibrillary tangles.