| 发明名称 |
Anti-alphavbeta6 antibodies |
| 摘要 |
<p>Disclosed are monoclonal antibodies that specifically bind to alphavbeta6 and inhibits the binding of alphavbeta6 to latency associated peptide (LAP) with an IC50 value lower than that of antibody 10D5. Also disclosed is the use of the antibody to treat a disease mediated by alphavbeta6.</p> |
| 申请公布号 |
NZ535425(A) |
申请公布日期 |
2008.05.30 |
| 申请号 |
NZ20030535425 |
申请日期 |
2003.03.13 |
| 申请人 |
BIOGEN IDEC MA INC.;THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
VIOLETTE, SHELIA M;WEINREB, PAUL H;SIMON, KENNETH J;SHEPPARD, DEAN;LEONE, DIANE R |
| 分类号 |
C12N15/09;A61K39/395;A61K47/48;A61K51/10;A61P1/16;A61P11/00;A61P13/12;A61P17/02;A61P17/06;A61P35/00;C07K7/08;C07K14/00;C07K16/18;C07K16/28;C12N;C12N5/10;C12N5/12;C12Q1/02;G01N33/574;G01N33/68;(IPC1-7):C12N5/00 |
主分类号 |
C12N15/09 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
