METHODS OF TREATING CHRONIC INFLAMMATORY DISEASES USING A GM-CSF ANTAGONIST

摘要

The invention is based on the discovery that GM-CSF antagonists can be us ed for the treatment of chronic inflammatory disease, such as rheumatoid art hirtis. Accordingly, the invention provides methods of administering a GM-CS F antagonist, e.g., a GM-CSF antibody, and an anti-folate compounds, e.g., m ethotrexate, to a patient that has RA and pharmaceutical compositions compri sing such antagonists.