摘要 |
This invention relates to an extended release formulation comprising a so lid non-steroidal non-ionized hydrophilic drug, having a molecular weight be low 500 Dalton and having a solubility of at least 0.1 wt% in ethylene vinyl acetate copolymer having a vinyl acetate content of 28%, which formulation is a vaginal device having a skin and which device comprises an inner compar tment made of a thermoplastic polymer, which polymer is containing the drug. The polymer is preferably made of ethylene-vinyl acetate copolymer.
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