| 发明名称 |
(R)-N-STEREOISOMERS OF 7,8-SATURATED-4,5-EPOXY-MORPHINANIUM ANALOGS |
| 摘要 |
<p>Novel (R)-N-stereoisomers of 7,8-saturated-4,5-epoxy-morphinanium analogs are disclosed. Pharmaceutical compositions containing the (R)-N-stereoisomers of 7,8-saturated-4,5-epoxy-morphinanium analogs and methods for their pharmaceutical uses are also disclosed. Such analogs are disclosed as being useful in treating, among varying conditions, opioid-induced constipation.</p> |
| 申请公布号 |
WO2008064351(A2) |
申请公布日期 |
2008.05.29 |
| 申请号 |
WO2007US85458 |
申请日期 |
2007.11.21 |
| 申请人 |
PROGENICS PHARMACEUTICALS, INC.;PEREZ, JULIO;HAN, AMI QI;ROTSHTEYN, YAKOV |
发明人 |
PEREZ, JULIO;HAN, AMI QI;ROTSHTEYN, YAKOV |
| 分类号 |
A61K31/485 |
主分类号 |
A61K31/485 |
| 代理机构 |
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