| 摘要 |
Disclosed are recombinant human tyrosinase, which the transmembrane domain of human tyrosinase is removed and a method of producing the same. The method includes expressing human tyrosinase gene, which C-terminal transmembrane domain of human tyrosinase is removed, and separating and purifying the expressed recombinant human tyrosinase. The method according to the present invention have effects on mass-producing the recombinant human tyrosinase having a good enzyme activity without forming insoluble inclusion body, a simple purifying process and a improved purifying yield.
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