BIODEGRADABLE DEVICE FOR INTRAOCULAR DRUG DELIVERY

摘要

This invention is related to the production process of a pharmaceutical formulation that can treat retinal degenerations and diseases of the posterior segment of the eye, such as diabetic retinopathy, age-related macular degeneration, retinitis by cytomegalovirus, endophthalmitis and uveitis. Said formulation comprises a monolithic system of the drug composed by a biodegradable matrix of a polymer of the polyester class. The said formulation is applicable for the intraocular route. This biodegradable device can deliver one or more drugs, such as dexamethasone, prednisolone and triamcinolone, nonsteroidal antiinflammatory drugs, antibiotics, immunosuppressive agents and antiproliferative agents.