Swine Cell For Xenotransplantation, Method of Selecting the Same and Swine For Xenotransplantation

摘要

The invention presents a swine cell not expressing alpha-1,3-galactosyl transferase and expressing human complement inhibitor and/or human N-acetyl glucosaminyl transferase III; a method of selecting the same; and a swine for xenotransplantation. The swine for xenotransplantation of the invention is very useful in inhibiting the acute rejection characteristic to xenotransplantation because it does not express alpha-Gal antigen but inhibits the progress of a complement reaction, if unexpectedly induced, and/or expresses little xenoantigen other than alpha-Gal antigen.