发明名称 Method for preparing microparticles having a selected polymer molecular weight
摘要 The present invention provides a method for preparing microparticles having a selected polymer molecular weight. The hold time and temperature of a solution containing a nucleophilic compound and a polymer having a starting molecular weight are controlled in order to control the molecular weight of the polymer in the finished microparticle product. In this manner, a selected polymer molecular weight in the finished microparticle product can be achieved from a variety of starting material molecular weights.
申请公布号 EP1925297(A1) 申请公布日期 2008.05.28
申请号 EP20080102276 申请日期 2001.04.19
申请人 ALKERMES, INC. 发明人 WRIGHT, STEVEN G;RICKEY, MICHAEL E.;RAMSTACK, MICHAEL J.;LYONS, SHAWN, L.;HOTZ, JOYCE, M.
分类号 A61K9/16;C07D489/08;A61K9/50;A61K31/216;A61K31/485;A61K31/519;A61K47/34;B01J13/02;C07D471/04;C08G63/06 主分类号 A61K9/16
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