发明名称 |
Method for preparing microparticles having a selected polymer molecular weight |
摘要 |
The present invention provides a method for preparing microparticles having a selected polymer molecular weight. The hold time and temperature of a solution containing a nucleophilic compound and a polymer having a starting molecular weight are controlled in order to control the molecular weight of the polymer in the finished microparticle product. In this manner, a selected polymer molecular weight in the finished microparticle product can be achieved from a variety of starting material molecular weights. |
申请公布号 |
EP1925297(A1) |
申请公布日期 |
2008.05.28 |
申请号 |
EP20080102276 |
申请日期 |
2001.04.19 |
申请人 |
ALKERMES, INC. |
发明人 |
WRIGHT, STEVEN G;RICKEY, MICHAEL E.;RAMSTACK, MICHAEL J.;LYONS, SHAWN, L.;HOTZ, JOYCE, M. |
分类号 |
A61K9/16;C07D489/08;A61K9/50;A61K31/216;A61K31/485;A61K31/519;A61K47/34;B01J13/02;C07D471/04;C08G63/06 |
主分类号 |
A61K9/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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