发明名称 |
Pharmaceutical formulations for dry powder inhalers comprising a low-dosage strength active ingredient |
摘要 |
The invention provides a formulation to be administered as dry powder for inhalation suitable for efficacious delivery of low-dosage strength active ingredients to the low respiratory tract of patient. In particular, the invention provides a formulation comprising microparticles constituted of microparticles of a low-dosage strength active ingredient and microparticles of an excipient wherein the MMD of the microparticles is comprised between 2 and 15 micron, at least 10% of the microparticles has a mass diameter (MD) higher than 0.5 micron, and the process of preparation thereof. |
申请公布号 |
ZA200607700(B) |
申请公布日期 |
2008.05.28 |
申请号 |
ZA20060007700 |
申请日期 |
2005.03.16 |
申请人 |
CHIESI FARMACEUTICI S.P.A. |
发明人 |
BILZI, ROBERTO;ARMANNI, ANGELA;RASTELLI, ROBERTO;COCCONI, DANIELA;MUSA, ROSSELLA |
分类号 |
A61K;A61K9/00;A61K9/14;A61K9/50;A61K31/4704 |
主分类号 |
A61K |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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