APPARATUS AND SYSTEM HAVING DRY CONTROL GENE SILENCING COMPOSITIONS

摘要

A reverse transfection apparatus can be used for introducing siRNA into a ce ll to effect gene silencing. Such an apparatus can include a well plate having a well configured for transfecting cells. The well can include a substantially dry gene silencing composition that has at least a first siRNA which silence s a first target gene. The gene silencing composition can be configured such that the at least first siRNA is capable of being solubilized or suspended i n an aqueous medium in an amount sufficient for transfecting cells in the well . Additionally, the at least first siRNA can include a modification or a conjugate. The reverse transfection apparatus can be provided as a kit or system that additionally includes cells, polynucleotide carriers, reverse transfection reagents, and the like.