IMMUNOGLOBULIN REMOVING SORBENT

摘要

FIELD: medicine; immunology. ^ SUBSTANCE: sorbent is offered to remove immunoglobulin from human blood plasma. This sorbent contains agarous matrix covalently combined with ligand. As a ligand at that it contains F(ab)2 fragments of specific affinely-purified polyclonal antibodies blocking human immunoglobulin G. Sorbent is actually biologically inert, biocompatible agarous matrix. Sorbent is characterized with higher sorptive capacity and safety of immunosorbents used practical purposes, specifically for therapeutic aphaeresis in comparison to well-known polyclonal bodies based sorbents. ^ EFFECT: considerable reduction of prospective immunological response of human body for foreign protein. ^ 1 ex, 1 tbl