发明名称 BENZENE DERIVATIVE OR SALT THEREOF
摘要 [PROBLEMS] To provide a compound which has an anticoagulation activity based on the inhibition of an activated blood coagulation factor X and is useful as a blood coagulation inhibitor or a preventive or therapeutic agent for a disease caused by thrombus or embolus. [MEANS FOR SOLVING PROBLEMS] A benzene derivative characterized by having a chemical structure in which a phenol ring and a benzene ring are bound via an amide bond and the phenol ring is further bound to a benzene ring or a heteroaryl ring via an amide bond or a salt thereof. These comounds have an excellent activated blood coagulation factor X inhibitory action and particularly has an excellent oral activity.
申请公布号 KR20080046711(A) 申请公布日期 2008.05.27
申请号 KR20087008720 申请日期 2008.04.11
申请人 ASTELLAS PHARMA INC. 发明人 HIRAYAMA FUKUSHI;FUJIYASU JIRO;KAGA DAISUKE;NEGORO KENJI;SASUGA DAISUKE;SEKI NORIO;SUZUKI KEN ICHI
分类号 C07D211/74;A61K31/435;C07D213/64;C07D413/14 主分类号 C07D211/74
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