| 摘要 |
PROBLEM TO BE SOLVED: To provide crystals of a salt of 4'-ä2-[(1S, 2R)-2-hydroxy-2-(4-hydroxyphenyl)-1-methylethylamino]ethoxy}-3-isopropyl-3', 5'-dimethylbiphenyl-4-carboxylic acid. SOLUTION: Theαtype,βtype andγtype crystals produced by treating hydrochloride of 4'-ä2-[(1S, 2R)-2-hydroxy-2-(4-hydroxyphenyl)-1-methylethyl-amino]ethoxy}-3-isopropyl-3', 5'-dimethylbiphenyl-4-carboxylic acid with specified solvents, which can be discriminated by the characteristic diffraction peaks of powder X-ray diffractometry and the like. COPYRIGHT: (C)2008,JPO&INPIT
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