MRI METHOD FOR QUANTIFICATION OF CEREBRAL PERFUSION

摘要

A method for calculating quantitative perfusion measurements using an MRI system includes a pulse sequence that acquires perfusion weighted images and additionally measures T₁ values before and after the administration of a contrast agent. T₁ values are measured by rapidly sampling a longitudinal relaxation curve and employed to determine the blood volume in tissue. A correction factor for the effect of water diffusion between blood vessels and the extravascular space is determined.