摘要 |
Compounds of the structure (I) are described, wherein R<SUB>1</SUB>, R<SUB>2</SUB>, R<SUB>5</SUB>, R<SUB>6</SUB>, V, X, Y, Z and Q are described herein, or a pharmaceutically acceptable salt, tautomer, metabolite or prodrug thereof. These compounds are useful for treating a variety of hormone-related conditions including contraception, treating or preventing fibroids, endometriosis, dysfunctional bleeding, uterine leiomyomata, polycystic ovary syndrome, or hormone-dependent carcinomas, providing hormone replacement therapy, stimulating food intake or synchronizing estrus. |
申请人 |
WYETH;COMMONS, THOMAS, JOSEPH;FENSOME, ANDREW;HEFFERNAN, GAVIN, DAVID;MCCOMAS, CASEY, CAMERON;WOODWORTH, RICHARD, PAGE, JR.;WEBB, MICHAEL, BYRON;MARELLA, MICHAEL, ANTHONY;MELENSKI, EDWARD, GEORGE;BERNOTAS, RONALD, CHARLES |
发明人 |
COMMONS, THOMAS, JOSEPH;FENSOME, ANDREW;HEFFERNAN, GAVIN, DAVID;MCCOMAS, CASEY, CAMERON;WOODWORTH, RICHARD, PAGE, JR.;WEBB, MICHAEL, BYRON;MARELLA, MICHAEL, ANTHONY;MELENSKI, EDWARD, GEORGE;BERNOTAS, RONALD, CHARLES |