发明名称 |
Control Of Feeding Behavior By Changing Neuronal Energy Balance |
摘要 |
Obesity is a worldwide health issue, affecting children and adults in developed and developing countries. Obesity is a disorder of both energy metabolism and appetite regulation, and may be understood as a dysfunction of energy balance. Applicants have found a means for regulating food intake by a subject by administering a compound to the subject which affects neuronal energy balance. Applicants have found a means for regulating food intake by a subject administering a compound to the subject which targets the activity of AMPK, in particular inhibiting activation, in particular hypothalamic. Applicants have also found a method of inducing weight loss in a subject by decreasing the subjects appetite by administering a compound to the subject which increases the subject's neuronal energy balance.
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申请公布号 |
US2008119548(A1) |
申请公布日期 |
2008.05.22 |
申请号 |
US20050593090 |
申请日期 |
2005.03.18 |
申请人 |
RONNETT GABRIELLE V;KUHAJDA FRANKCIS P;THUPARI JAGAN N;LANDREE LESLIE E;MORAN TIMOTHY H;KIM EUN-KYOUNG |
发明人 |
RONNETT GABRIELLE V.;KUHAJDA FRANKCIS P.;THUPARI JAGAN N.;LANDREE LESLIE E.;MORAN TIMOTHY H.;KIM EUN-KYOUNG |
分类号 |
A61K31/341;A61K31/34;A61K31/70;A61P3/04 |
主分类号 |
A61K31/341 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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