发明名称 |
Method of growing bacteria to deliver bioactive compounds to the intestine of ruminants |
摘要 |
Methods for increasing the resistance to rumen inactivation of a cultured Gram positive bacteria strain useful for gastrointestinal delivery of bioactive compounds to ruminants, which includes the steps of growing a culture of the bacteria strain through at least one passage in a growth medium containing an amount of lysozyme effective to induce the growth of bacterial cell walls resistant to protozoal predation; and recovering the bacteria strain from the lysozyme-containing medium. Rumen-bypass feed supplements produced by the inventive method are also disclosed, as well as methods for supplementing the diet of a ruminant with the rumen bypass feed supplements and an in vitro method for evaluating the resistance of Gram positive bacteria strains to rumen inactivation in vivo.
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申请公布号 |
US2008118472(A1) |
申请公布日期 |
2008.05.22 |
申请号 |
US20050295853 |
申请日期 |
2005.12.06 |
申请人 |
SAGE BIOSCIENCES INC. |
发明人 |
RODE LYLE M.;NEWBOLD C. JAMES |
分类号 |
A61K35/74;C12N1/21;C12P13/08 |
主分类号 |
A61K35/74 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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