发明名称 |
DIARYL, DIPYRIDINYL AND ARYL-PYRIDINYL DERIVATIVES AND USES THEREOF |
摘要 |
Compounds of Formula (I) that act as antagonists at the mu, kappa and/or delta opioid receptors and therefore useful in the treatment of diseases, conditions and/or disorders that benefit from such antagonism in animals are described herein. Formula (I) where R, R<SUP>1</SUP>, R<SUP>2a</SUP>, R<SUP>2b</SUP>, R<SUP>3</SUP>, R<SUP>4</SUP>, V, R<SUP>6</SUP>, R<SUP>7</SUP>, R<SUP>8</SUP>, R<SUP>9</SUP>, W and X are described herein. |
申请公布号 |
WO2008059335(A1) |
申请公布日期 |
2008.05.22 |
申请号 |
WO2007IB03393 |
申请日期 |
2007.11.01 |
申请人 |
PFIZER PRODUCTS INC.;MAGNUS-ARYITEY, GEORGE TETTEH;RUGGERI, ROGER BENJAMIN;THUMA, BENJAMIN AARON |
发明人 |
MAGNUS-ARYITEY, GEORGE TETTEH;RUGGERI, ROGER BENJAMIN;THUMA, BENJAMIN AARON |
分类号 |
C07C237/28;A61K31/166;A61K31/18;A61K31/44;A61P3/04;C07C311/08;C07D209/44;C07D213/24;C07D231/12;C07D235/26;C07D277/28;C07D295/20;C07D307/00;C07D311/58;C07D317/32 |
主分类号 |
C07C237/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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