| 摘要 |
The present invention provides compositions and methods useful for preparing and using analogs, derivatives, and modifications of kaempferols that have anti-neoplastic activity. More specifically, the compounds are analogs, derivatives, and modifications of SLO1O1. The invention further provides compounds that are inhibitors of RSK activity. The invention further provides compounds that selectively inhibit excessive RSK activity in cancers. The present invention further provides methods for treating cancer using compounds of the invention. |
| 申请人 |
UNIVERSITY OF VIRGINIA PATENT FOUNDATION;SMITH, JEFFREY, A.;HECHT, SIDNEY, M.;LANNIGAN-MACARA, DEBORAH, A.;MALONEY, DAVID, J. |
发明人 |
SMITH, JEFFREY, A.;HECHT, SIDNEY, M.;LANNIGAN-MACARA, DEBORAH, A.;MALONEY, DAVID, J. |
