REAGENT AND USE THEREOF FOR THE PRODUCTION OF BISPHOSPHONATES
摘要
<p>A new liquid reagent is disclosed in form of an ionic liquid containing phosphorous acid and a tertiary amine. The reagent can be used as a replacement of phosphorous acid, where the new reagent as a liquid reagent can be handled using usual equipment for handling liquids and the dosing of the reagent can therefore be controlled more precisely in industrial plants compared to phosphorous acid, which is a solid at ambient temperature. The new liquid reagent is particular suitable for the synthesis of bisphosphonates.</p>
申请公布号
WO2008058722(A1)
申请公布日期
2008.05.22
申请号
WO2007EP09841
申请日期
2007.11.14
申请人
SANDOZ A/S;LERSTRUP, KNUD;PREIKSCHAT, HERBERT, FRITZ;FISCHER, ERIK
发明人
LERSTRUP, KNUD;PREIKSCHAT, HERBERT, FRITZ;FISCHER, ERIK