发明名称 Layered pharmaceutical formulations comprising an intermediate rapidly dissolving layer
摘要 In one embodiment a layered pharmaceutical formulation includes two or more pharmaceutical layers and an intermediate layer disposed between at least two of the two or more pharmaceutical layers, the intermediate layer configured to dissolve in vivo to thereby leave the two or more pharmaceutical layers substantially intact. In one embodiment, an active pharmaceutical ingredient in at least one of the pharmaceutical layers is selected from bupropion, zonisamide, naltrexone, topiramate, phentermine, metformin, olanzapine and fluoxetine.
申请公布号 AU2007319471(A1) 申请公布日期 2008.05.22
申请号 AU20070319471 申请日期 2007.11.08
申请人 OREXIGEN THERAPEUTICS, INC. 发明人 RICK SOLTERO;ANTHONY A. MCKINNEY;GARY TOLLEFSON;ECKARD WEBER
分类号 A61K9/24;A61K31/00;A61K31/137;A61K31/138;A61K31/155;A61K31/35;A61K31/423;A61K31/485;A61K31/5513 主分类号 A61K9/24
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