| 发明名称 |
INHIBITOR OF IMPDH ENZYME |
| 摘要 |
PROBLEM TO BE SOLVED: To provide a compound which inhibits IMPDH and to provide a pharmaceutical composition containing the compound. SOLUTION: The compound and the pharmaceutical composition are particularly well suited for inhibiting IMPDH enzyme activity and consequently, may be advantageously use as therapeutic agents for IMPDH-mediated processes. This invention also relates to a method for inhibiting the activity of IMPDH by using the compound and a related compound. COPYRIGHT: (C)2008,JPO&INPIT
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| 申请公布号 |
JP2008115186(A) |
申请公布日期 |
2008.05.22 |
| 申请号 |
JP20070316708 |
申请日期 |
2007.12.07 |
| 申请人 |
VERTEX PHARMACEUT INC |
发明人 |
STAMOS DEAN;TRUDEAU MARTIN;BETHIEL SCOTT;BADIA MICHAEL;SAUNDERS JEFFREY |
| 分类号 |
C07C275/42;C07D307/20;A61K31/27;A61K31/275;A61K31/341;A61K31/421;A61K31/422;A61K31/454;A61K31/5377;A61K31/541;A61K45/00;A61P1/18;A61P9/10;A61P11/00;A61P11/06;A61P19/02;A61P29/00;A61P31/12;A61P31/14;A61P35/00;A61P35/02;A61P37/02;A61P37/06;A61P43/00;C07C275/40;C07D263/32;C07D413/12;C07D417/12;C07F9/653 |
主分类号 |
C07C275/42 |
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