发明名称 |
Treatment of neurodegenerative conditions |
摘要 |
The use of a defined structure lipid glyceride comprising a glycerol moiety esterifed with one or more fatty acid moieties, characterised in that the lipid has a fatty acid moiety at the sn-2 position selected from the group consisting of q -linolenic acid and dihomo- q -linolenic acid for the manufacture of a medicament for the treatment of a neurodegenerative disease is provided characterised in that it is a lipid of formula II <EMI ID=1.1 HE=31 WI=24 LX=603 LY=1046 TI=CF> <PC>```wherein <DL TSIZE=10> <DT>R<1> and R<3><DD>are the same and are selected from H, -C(O)(CH2)nCH3 wherein n is selected from 4 to 16, and <DT>R<2><DD>is selected from q -linolenoyl and dihomo- q -linolenoyl-residues. </DL> characterised in that the medicament is for daily dosing at between 1 and 20 grams of he lipid glyceride. |
申请公布号 |
GB2442164(B) |
申请公布日期 |
2008.05.21 |
申请号 |
GB20070025392 |
申请日期 |
2004.08.13 |
申请人 |
BTG INTERNATIONAL LIMITED |
发明人 |
MICHAEL J LEACH;LAURENCE S HARBIGE;MOHAMMED SHARIEF |
分类号 |
A61K31/232;A61P25/16;A61P25/28;C07C67/14;C07C67/29;C07C69/587;C07C69/65 |
主分类号 |
A61K31/232 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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