发明名称 DIARYLMETHYLIDENEPIPERIDINE DERIVATIVES, THEIR APPLICATION, METHODS AND INTERMEDIATE COMPOUND FOR THEIR PRODUCTION
摘要 FIELD: chemistry. ^ SUBSTANCE: invention covers new compounds of formula I or its salts suitable for pharmacology: , where R1 is selected from phenyl, pyridyl, thienyl, difurylglyoxal, imidazolyl, pyrrolyl and thiazolyl; R2, R3 and R4 independently are d-zalkyl or halogenated C1-zalkyl; and R5 is hydrogen. And also new intermediate compounds formula III: , where R2, R3 and R4 independently are C1-3alkyl or halogenated C1-6alkyl; and R5 is hydrogen. Invention also covers method of production of compound formula I and their applications. ^ EFFECT: production of new biologically active compounds. ^ 12 cl, 9 ex, 2 tbl
申请公布号 RU2324680(C2) 申请公布日期 2008.05.20
申请号 RU20050121491 申请日期 2004.01.13
申请人 ASTRAZENEKA AB 发明人 BRAUN UIL'JAM;GRIFFIN EHNDRJU;UOLPOL KRISTOFER
分类号 C07D211/70;A61K;A61K31/427;A61K31/433;A61K31/44;A61K31/4436;A61P1/00;A61P25/24;A61P29/00;C07D;C07D211/68;C07D401/06;C07D405/06;C07D409/06;C07D417/06 主分类号 C07D211/70
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