发明名称 Transgenic avians with an ovomucoid gene expression control region linked to a nucleotide sequence encoding a heterologous polypeptide
摘要 The present invention provides novel isolated nucleic acids that comprise an avian nucleic acid sequence comprising a ovomucoid gene expression control region. The ovomucoid promoter region of the present invention will allow expression of an operably linked heterologous nucleic acid insert in a transfected avian cell such as, for example, an oviduct cell. The isolated avian ovomucoid of the present invention may be operably linked with a selected nucleic acid insert, wherein the nucleic acid insert encodes a polypeptide desired to be expressed in a transfected cell. The recombinant DNA of the present invention may further comprise a polyadenylation signal sequence. The present invention further includes expression vectors comprising an isolated avian ovomucoid gene expression control region of the present invention, and transfected cells and transgenic avians comprising the expression vectors.
申请公布号 US7375258(B2) 申请公布日期 2008.05.20
申请号 US20040496731 申请日期 2004.05.21
申请人 AVIGENICS, INC. 发明人 HARVEY ALEX J.;WANG YOULIANG
分类号 A01K67/027;A01K67/00;C07K14/56;C07K14/81;C12N1/15;C12N1/19;C12N5/10;C12N15/00;C12N15/09;C12N15/11;C12N15/85 主分类号 A01K67/027
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