发明名称 НОВЫЕ ПРОИЗВОДНЫЕ 2-(1-АЗА-БИЦИКЛО[2.2.2]ОКТ-3-ИЛ)-2,3-ДИГИДРОИЗОИНДОЛ-1-ОНА/5,6-ДИГИДРО-ФУРО[2, 3-С]ПИРРОЛ-4-ОНА В КАЧЕСТВЕ ЛИГАНДОВ К АЛЬФА 7 НИКОТИНОВОМУ АЦЕТИЛХОЛИНОВОМУ РЕЦЕПТОРУ
摘要 This invention encompasses nicotinic acetylcholine receptor reactive compounds in accord with formula (I) Wherein: D represents O; E represents CH2, NH, O or S; n is 1 or 2 and stereoisomers, enantiomers, in vivo-hydrolysable precursors and pharmaceutically-acceptable salts of such compounds, pharmaceutical compositions and formulations containing them, methods of using them to treat diseases and conditions either alone or in combination with other therapeutically-active compounds or substances, processes and intermediates used to prepare them, uses of them as medicaments, uses of them in the manufacture of medicaments and uses of them for diagnostic and analytic purposes.
申请公布号 RU2006135481(A) 申请公布日期 2008.05.20
申请号 RU20060135481 申请日期 2005.04.06
申请人 АстраЗенека АБ (SE) 发明人 ЧАПДЕЛЕЙН Марк (US);ХЕРЗОГ Кейт Дж. (US)
分类号 C07D453/02;A61K;A61K31/439;A61P25/00;C07D209/46;C07D491/04;C07D519/00 主分类号 C07D453/02
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