| 发明名称 |
METHOD OF RISK PREDICTION OF BRONCHIAL ASTHMA |
| 摘要 |
FIELD: medicine; pulmonology. ^ SUBSTANCE: lymphocyte DNA of peripheral venous blood is studied. The genotypes and alleles of interleukin 4 polymorphic genes are determined by DNA synthesis polymerase chain reaction with following restriction enzyme digest analysis, in subjects. If IL4*T allele of the promoter polymorphism -590 C>T of IL4 gene in Tatar, and genotype *Ile50/*Ile50 polymorphism Ile50Val of IL4Ra gene in Russian are revealed, the risk of bronchial asthma is predicted. ^ EFFECT: precision and impartiality of disease prediction are increased. ^ 2 dwg, 2 tbl, 2 ex |
| 申请公布号 |
RU2324937(C1) |
申请公布日期 |
2008.05.20 |
| 申请号 |
RU20060141964 |
申请日期 |
2006.11.27 |
| 申请人 |
INSTITUT BIOKHIMII I GENETIKI UFIMSKOGO NAUCHNOGOTSENTRA ROSSIJSKOJ AKADEMII NAUK (IBG UNTS RAN);GOSUDARSTVENNOE OBRAZOVATEL'NOE UCHREZHDENIE VYSSHEGO PROFESSIONAL'NOGO OBRAZOVANIJA "BASHKIRSKIJ GOSUDARSTVENNYJ MEDITSINSKIJ UNIVERSITET FEDERAL'NOGO AGENTSTVA PO ZDRAVOOKHRANENIJU I SOTSIAL'NOMU RAZVITIJU" (GOU VPO BGMU ROSZDRAVA) |
发明人 |
KARUNAS ALEKSANDRA STANISLAVOVNA;SHALUKHINA ANITA RINATOVNA;ZAGIDULLIN SHAMIL' ZARIFOVICH;ISLAMGULOV DENIS VLADIMIROVICH;KHUSNUTDINOVA EHL'ZA KAMILEVNA |
| 分类号 |
G01N33/48;C12Q1/68 |
主分类号 |
G01N33/48 |
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