发明名称 |
NF-kB inhibitors and uses thereof |
摘要 |
A diastereomers of imidazolines as 4-position acids are described. The imidazoline diastereomers potentiate the activity of antitumor drugs and are potent inhibitors of the transcription factor NF-kappaB. |
申请公布号 |
US2008114015(A1) |
申请公布日期 |
2008.05.15 |
申请号 |
US20060435169 |
申请日期 |
2006.05.16 |
申请人 |
BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY |
发明人 |
TEPE JETZE J. |
分类号 |
A61K31/4164;A61K31/4375;A61K31/4439;A61P29/00;A61P31/00;A61P35/00;A61P37/00;C07D233/28;C07D401/04;C12N5/00 |
主分类号 |
A61K31/4164 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|