PROCESSES FOR THE HYDROGENATION OFa,ß- UNSATURATED KETONES

摘要

The catalytic hydrogenation of a.ß-unsaturated Ketones R<SUP>1</SUP> -CH=CH-CO-R<SUP>2</SUP> in which R<SUP>1</SUP> and R<SUP>2</SUP> Independently of one another represent straight-chain or branched C<SUB>1</SUB>-C<SUB>12-</SUB>alkyl or C<SUB>2</SUB>-C<SUB>12</SUB>-hydroxyalkyl; straight-chain or branched C<SUB>2</SUB>-C<SUB>12</SUB>-alkenyl, C<SUB>3-</SUB>C<SUB>8</SUB>-cyc[oatkyi, C<SUB>3</SUB>-C<SUB>8</SUB>-cycloalkenyl, C<SUB>7</SUB>-C<SUB>14</SUB>- aralkyl or C<SUB>6</SUB>-C<SUB>12</SUB>-aryl, where at least one of R<SUP>1</SUP> and R<SUP>2</SUP> is rnonosubstituted to trisubstituted by halogen, to give the respective saturated ketones R<SUP>11</SUP>-CH<SUB>2</SUB>-CH<SUB>2</SUB>-COR<SUP>12</SUP> in which R<SUP>11</SUP> and R<SUP>12</SUP> assume the meaning of R<SUP>1</SUP> and R<SUP>2</SUP> with the exception that alkenyl and cycloalkenyl are hydrogenated to the respective alkyl or cycloalkyl, wherein the hydrogenation process comprises combining the a.ß-unsaturated ketones and alcohol; the hydrogenation is carried out in the presence of (i) basic substance, (ii) Ni-containsng catalyst, and (iii) organic sulphur compound to produce product comprising the saturated ketones, the Ni-containing catalyst, and the alcohol and/or water, and the process further comprises filtering at least a portion of the Ni-containing catalyst from the product to produce filtered product; adding basic substance to the filtered product to produce an end product comprising the saturated ketones, alcohol and/or water, an inorganic chloride, and an amine; distilling at least a portion of the alcohol and at least a portion of tlie water from the end product; and filtering at least a portion of the inorganic chloride from the end product