发明名称 THIAZOLE AND OXAZOLE-SUBSTITUTED ARYLAMIDES
摘要 Compounds of the formula (I) or a pharmaceutically acceptable salt thereo f, wherein: R1 is a group of formula A or formula B; and X, R2, R3, R4, R5, R6, Ra and Rb are as defined herein. Also provided are methods of using the compounds for treating diseases mediated by a P2X3 and/or a P2X2/3 receptor antagonist and methods of making the subject compounds.
申请公布号 CA2668399(A1) 申请公布日期 2008.05.15
申请号 CA20072668399 申请日期 2007.10.31
申请人 F. HOFFMANN-LA ROCHE AG 发明人 YANG, MINMIN;HAWLEY, RONALD CHARLES;CHEN, LI;DILLON, MICHAEL PATRICK;FENG, LICHUN
分类号 C07D263/32;A61K31/19;A61P13/00;C07D277/30;C07D277/66;C07D401/14 主分类号 C07D263/32
代理机构 代理人
主权项
地址