发明名称 |
THIAZOLE AND OXAZOLE-SUBSTITUTED ARYLAMIDES |
摘要 |
Compounds of the formula (I) or a pharmaceutically acceptable salt thereo f, wherein: R1 is a group of formula A or formula B; and X, R2, R3, R4, R5, R6, Ra and Rb are as defined herein. Also provided are methods of using the compounds for treating diseases mediated by a P2X3 and/or a P2X2/3 receptor antagonist and methods of making the subject compounds.
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申请公布号 |
CA2668399(A1) |
申请公布日期 |
2008.05.15 |
申请号 |
CA20072668399 |
申请日期 |
2007.10.31 |
申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
YANG, MINMIN;HAWLEY, RONALD CHARLES;CHEN, LI;DILLON, MICHAEL PATRICK;FENG, LICHUN |
分类号 |
C07D263/32;A61K31/19;A61P13/00;C07D277/30;C07D277/66;C07D401/14 |
主分类号 |
C07D263/32 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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