发明名称 Melt-processed imatinib dosage form
摘要 The invention provides a dosage form, comprising a melt-processed mixture of (a) a pharmaceutically effective amount of imatinib or a salt thereof, (b) at least one polymeric binder, and (c) at least one pharmaceutically acceptable non-ionic surfactant. The invention provides imatinib dosage forms with high drug loading which can be prepared in a simple and efficient manner, imatinib dosage forms from which the active principle is released in an essentially pH-independent fashion, and extended release imatinib dosage forms.
申请公布号 AU2007316557(A1) 申请公布日期 2008.05.15
申请号 AU20070316557 申请日期 2007.11.08
申请人 ABBOTT GMBH & CO. KG;NOVARTIS AG 发明人 HARALD HACH;ULRICH WESTEDT;RALF ALTENBURGER;NORBERT STEIGER;NICOLETTA LOGGIA;JORG OGORKA;JORG BREITENBACH;MARTIN KNOBLOCH
分类号 A61K9/20;A61K31/505 主分类号 A61K9/20
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