摘要 |
A method includes providing a sample containing at least one whole, intact particle or organism in a container; creating a mixture comprising the sample, at least one magnetically-responsive particle, and a remainder; and providing the mixture with a pH of less than about 7.0. By providing the mixture with a pH of less than about 7.0, alteration of the surface charge properties of at least the one magnetic particle occurs, thereby causing the at least one whole, intact particle or organism to become non-specifically bound to the at least one magnetically-responsive particle to form a complex.
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