发明名称 6-Alkylamino-2-methyl-2'-(N-methyl substituted sulfonamido)methyl-2H-1-benzopyran derivative as anti-inflammatory inhibitor
摘要 The present invention relates to a noble 6-alkylamino-2-methyl-2'-(N-methyl substituted sulfonamido)methyl-2H-1-benzopyran derivative, a method for preparing the same with high efficiency using a parallel synthetic method, one of combinatorial chemical synthetic techniques, and a use of the novel compound showing a high inhibitory effect to 5-lipoxygenase (5-LO) activity for preventing and treating leukotriene (LTA4, B4, C4, D4) activation-related diseases such as inflammatory diseases, rheumatoid arthritis, colitis, asthma and psoriasis.
申请公布号 US7371874(B2) 申请公布日期 2008.05.13
申请号 US20060491320 申请日期 2006.07.21
申请人 KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY 发明人 GONG YOUNG-DAE;CHEON HYAE-GYEONG;JEON MOON-KOOK;SIK CHO YOUNG;HWANG JONG YEON;SUB CHOI HYUNG;SUK JEON HYUN;HWANG SOON-HEE;SOOK SONG JIN;HYUN KIM CHI;YOO SUNG-EUN
分类号 C07D311/00;A61K31/35;A61K31/46;C07D405/00 主分类号 C07D311/00
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