发明名称 |
Process for the biological production of 1,3-propanediol with high yield |
摘要 |
The present invention provides a microorganism useful for biologically producing 1,3-propanediol from a fermentable carbon source at higher yield than was previously known. The complexity of the cofactor requirements necessitates the use of a whole cell catalyst for an industrial process that utilizes this reaction sequence to produce 1,3-propanediol. The invention provides a microorganism with disruptions in specified genes and alterations in the expression levels of specified genes that is useful in a higher yielding process to produce 1,3-propanediol. |
申请公布号 |
US7371558(B2) |
申请公布日期 |
2008.05.13 |
申请号 |
US20030680286 |
申请日期 |
2003.10.06 |
申请人 |
E.I. DU PONT DE NEMOURS AND COMPANY;GENENCOR INTERNATIONAL |
发明人 |
CERVIN MARGUERITE A.;SOUCAILLE PHILLIPE;VALLE FERNANDO |
分类号 |
C12N1/21;C07H21/04;C12N;C12N1/00;C12N15/54;C12N15/70;C12N15/74;C12P7/04;C12P7/18;C12P7/20;C12P13/04;C12P21/06;C12Q1/68 |
主分类号 |
C12N1/21 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|