发明名称 Benzothiazole derivatives
摘要 This invention relates to compounds of formula I wherein R<SUP>1 </SUP>and R<SUP>2 </SUP>are defined herein, or a pharmaceutically acceptable salt thereof. It has been found that the compounds of formula I are adenosine receptor ligands with good affinity to the A<SUB>2A</SUB>-receptor and a high selectivity to the A<SUB>1</SUB>- and A<SUB>3 </SUB>receptors. These compounds are useful, inter alia, in treatment of Alzheimer's disease, depression, Parkinson's disease and ADHD.
申请公布号 US7371748(B2) 申请公布日期 2008.05.13
申请号 US20040847558 申请日期 2004.05.17
申请人 HOFFMAN-LA ROCHE INC. 发明人 FLOHR ALEXANDER;JAKOB-ROETNE ROLAND;NORCROSS ROGER DAVID;RIEMER CLAUS
分类号 C07D413/14;A61K31/428;A61K31/4436;A61K31/5377;A61P25/28;C07D277/82;C07D417/02;C07D417/04;C07D417/14;C07D491/10 主分类号 C07D413/14
代理机构 代理人
主权项
地址