发明名称 |
Targeted glycosaminoglycan polymers by polymer grafting and methods of making and using same |
摘要 |
The present invention relates to methodology for polymer grafting by a polysaccharide synthase and, more particularly, polymer grafting using the hyaluronate or chondroitin or heparin/heparosan synthases from Pasteurella, in order to create a variety of glycosaminoglycan oligosaccharides having a natural or chimeric or hybrid sugar structure with a targeted size that are substantially monodisperse in size. The present invention also relates to methodology for polymer grafting by a polysachharide synthase to form glycosaminoglycan polymers having an unnatural structure.
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申请公布号 |
US2008108110(A1) |
申请公布日期 |
2008.05.08 |
申请号 |
US20070906676 |
申请日期 |
2007.10.03 |
申请人 |
DEANGELIS PAUL L;SISMEY-RAGATZ ALISON |
发明人 |
DEANGELIS PAUL L.;SISMEY-RAGATZ ALISON |
分类号 |
C12P19/26;C07H5/04;G06Q30/00 |
主分类号 |
C12P19/26 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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