发明名称 Methods and Compositions Relating to Ccr5 Antagonist, Inf-Y and Il-13 Induced Inflammation
摘要 The present invention includes compositions and methods for the treatment of Th1 and/or Th2 medicated inflammatory diseases, relating to inhibiting CCR5. This is because the present invention demonstrates, for the first time, that expression of IFN-gamma, IL-13, and CCR5 mediates and/or is associated with Th1 and/or Th2 inflammatory diseases and that inhibiting CCR5 treats, and even prevents, the diseases. Thus, the Invention relates to the novel discovery that inhibiting CCR5 treats and prevents Th1 and/or Th2 mediated inflammatory disease.
申请公布号 US2008107647(A1) 申请公布日期 2008.05.08
申请号 US20040582610 申请日期 2004.12.13
申请人 MA BING;ELIAS JACK A 发明人 MA BING;ELIAS JACK A.
分类号 A61K39/395;A61K;A61K31/70;A61P43/00;C07K16/28 主分类号 A61K39/395
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