发明名称 |
METHOD FOR THE PREPARATION OF OPTICALLY ACTIVE 2-SULFONYLOXY-1-PHENYLETHANOL DERIVATIVES |
摘要 |
Optically active 2-sulfonyloxy-1-phenylethanol derivative of formula (II) can be prepared easily and selectively by the method of the present invention using an asymmetric reduction of an a-sulfonyloxy acetophenone compound with a rhodium catalyst having petamethylcyclopentadienyl group and a hydrogen donor, and the compound of formula (II) obtained in the inventive method exhibits a higher e.e. (enantiomer excess) value than that of the products in the conventional methods. |
申请公布号 |
WO2008054155(A1) |
申请公布日期 |
2008.05.08 |
申请号 |
WO2007KR05492 |
申请日期 |
2007.11.01 |
申请人 |
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY;LEE, KEE-IN;LEE, DO-MIN |
发明人 |
LEE, KEE-IN;LEE, DO-MIN |
分类号 |
C07C309/66 |
主分类号 |
C07C309/66 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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