摘要 |
The invention provides fusion proteins comprising an exendin-4 fused to a transferrin (Tf) via a polypeptide linker, as well as corresponding nucleic acid molecules, vectors, host cells, and pharmaceutical compositions. The invention also provides the use of the exendin-4/Tf fusion proteins for treatment of Type Il diabetes, obesity, and to reduce body weight. |
申请人 |
BIOREXIS PHARMACEUTICAL CORPORATION;SADEGHI, HOMAYOUN;PRIOR, CHRISTOPHER, PHILIP;BALLANCE, DAVID, JAMES;TURNER, ANDREW, JOHN |
发明人 |
SADEGHI, HOMAYOUN;PRIOR, CHRISTOPHER, PHILIP;BALLANCE, DAVID, JAMES;TURNER, ANDREW, JOHN |