| 摘要 |
The present invention provides a marker, kit and method for determining the level of axon outgrowth and/or fasciculation, or conditions, disorders or diseases associated with the level of axon outgrowth and/or fasciculation. The present invention was achieved by unexpectedly finding the relationship between DISC1 and FEZ1 and KIAA0844 and unexpectedly finding that axon outgrowth and/or fasciculation are not normally conducted if the normal binding therebetween was inhibited. Therefore, the present invention relates to an agent specifically interacting with DISC1 and a gene product thereof, an agent specifically binding FEZ1 and a gene product thereof, an agent specifically binding FEZ1 and a gene product thereof, and an agent specifically binding KIAA0844 and a gene product thereof.
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