发明名称 Phenylacetic acid compounds
摘要 The present invention provides a process for the preparation 6-[3-(hetero)aryloxy-2-fluoro-benzyl]-2H-pyridazin-3-one compounds 1 where R2 is an optionally substituted aryl or an optionally substituted heteroaryl, R<SUP>6 </SUP>is NO<SUB>2</SUB>, NH<SUB>2</SUB>, alkyl, halogen, or a function group readily derived therefrom and R<SUP>4c </SUP>is hydrogen or alkyl. There also is provided a process for the preparation of phenylacetic acid compounds 2, wherein R<SUP>2 </SUP>and R<SUP>6 </SUP>are as defined previously and R<SUP>5a </SUP>is hydrogen or alkyl, which are useful for the preparation of pyridazinone compounds.
申请公布号 US2008108810(A1) 申请公布日期 2008.05.08
申请号 US20070977262 申请日期 2007.10.23
申请人 ROCHE PALO ALTO LLC 发明人 KERTESZ DENIS J.;MARTIN MICHAEL;PALMER WYLIE S.
分类号 C07D237/14;C07C205/56;C07C235/46;C07C255/54;C07C255/57;C07D209/08;C07D213/65;C07D237/02;C07D401/02;C07D401/12;C07D403/12 主分类号 C07D237/14
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