发明名称 |
COMPOSITION FOR TREATMENT OF CERVIX CANCER |
摘要 |
A composition for treating cancer is provided to show excellent cancer treating effect compared to treatment by a human papilloma virus(HPV) specific siRNA only or an anti-cancer agent only and prevent side effects caused by a highly concentrated anti-cancer agent by using a lowly concentrated anti-cancer agent. A composition for treating cervix cancer comprises a first active part including an HPV specific siRNA as an effective ingredient and a second active part including a lowly concentrated anti-cancer agent such as cisplatin, heptaplatin, carboplatin or riboplatin, wherein the HPV specific siRNA includes a sequence described as SEQ ID : NOs. 1 or 3 to 14. A method for treating cancer comprises the steps of: (a) administering an effective amount of the HPV specific siRNA at one or two times for 24 hours to a patient; and (b) administering an effective amount of the lowly concentrated anti-cancer agent to the patient for 4-7 days. Further, a concentration of the anti-cancer agent is 0.625 to 160 muM.
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申请公布号 |
KR20080040412(A) |
申请公布日期 |
2008.05.08 |
申请号 |
KR20060108352 |
申请日期 |
2006.11.03 |
申请人 |
SEOUL NATIONAL UNIVERSITY INDUSTRY FOUNDATION |
发明人 |
SHIN, YOUNG KEE;JUNG, HUN SOON;OH, YU KYOUNG;LEE, JUNG HYUN |
分类号 |
A61K35/76;A61P35/00;C12N15/113 |
主分类号 |
A61K35/76 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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