发明名称 IL-17 RECEPTOR A ANTIGEN BINDING PROTEINS
摘要 The present invention relates to IL-17 Receptor A (IL-17RA or IL-17R) antigen binding proteins, such as antibodies, polynucleotide sequences encoding said antigen binding proteins, and compositions and methods for diagnosing and treating diseases mediated by IL-17 Receptor A activation by one or more IL-17 ligands. The present invention relates to the identification of neutralizing determinants on IL-17 Receptor A (IL-17RA or IL-17R) and antibodies that bind thereto. Aspects of the invention also include antibodies that compete for binding with the IL-17RA neutralizing antibodies described herein.
申请公布号 WO2008054603(A2) 申请公布日期 2008.05.08
申请号 WO2007US21174 申请日期 2007.10.01
申请人 AMGEN INC.;TOCKER, JOEL;PESCHON, JACQUES, J.;FITZPATRICK, DAVID;SMOTHERS, JAMES, F.;MEHLIN, CHRISTOPHER;LIM, AI CHING 发明人 TOCKER, JOEL;PESCHON, JACQUES, J.;FITZPATRICK, DAVID;SMOTHERS, JAMES, F.;MEHLIN, CHRISTOPHER;LIM, AI CHING
分类号 C07K16/00 主分类号 C07K16/00
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