| 摘要 |
<p>The claimed invention provides 1H-pyridine-2-one derivatives, inhibitors of PAI-1, processes for their preparation, pharmaceutical compositions containing them and their use in therapy. The compounds of Formula I, II and III may be used in the treatment of for example thrombosis, coronary heart disease, renal fibrosis, atherosclerotic plaque formation, cancer, diabetes and obesity.</p> |
| 申请人 |
ASTRAZENECA AB;ALMQVIST, FREDRIK;CHORELL, ERIK;DAS, PRALAY;EMTENAES, HANS;FJELLSTROEM, OLA;MOGEMARK, MICKAEL;POLLA, MAGNUS;AABERG, VERONICA |
发明人 |
ALMQVIST, FREDRIK;CHORELL, ERIK;DAS, PRALAY;EMTENAES, HANS;FJELLSTROEM, OLA;MOGEMARK, MICKAEL;POLLA, MAGNUS;AABERG, VERONICA |
