发明名称 |
IMPROVED MVA VACCINES |
摘要 |
<p>Recombinant modified vaccinia Ankara vectors are provided having a null mutation in a gene necessary for replication of the recombinant modified vaccinia Ankara virus and at least one heterologous antigen. The disclosed vectors optionally encode at least one pro-apoptotic factor, at least one anti-apoptotic factor, at least one immunomodulator, and combinations thereof. Cells complementing the null mutation the disclosed vectors are also provided.</p> |
申请公布号 |
EP1678292(A4) |
申请公布日期 |
2008.05.07 |
申请号 |
EP20040788867 |
申请日期 |
2004.09.20 |
申请人 |
EMORY UNIVERSITY |
发明人 |
FEINBERG, MARK, M.D.;GARBER, DAVID |
分类号 |
C12N5/10;A61K39/21;C07K14/16;C12N;C12N7/00;C12N7/01;C12N7/02;C12N15/863 |
主分类号 |
C12N5/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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