发明名称 FGFR4 promotes cancer cell resistance in response to chemotherapeutic drugs
摘要 <p>The present invention relates to Fibroblast-Growth Factor Receptor 4 (FGRF4) inhibitors for co-administration with a therapeutic procedure or/and agent for the prevention, alleviation or/and treatment of a hyperproliferative disorder, e.g. cancer, such as chemotherapy resistant cancer. Further, the present invention relates to a diagnostic procedure wherein expression status and/or polymorphisms of the FGFR4 gene are determined in a patient suffering from a hyperproliferative disorder, e.g. cancer. Based on the results of this determination and the status of the disorder to be treated a therapeutic protocol may be developed. Yet another subject of the present invention is a screening method.</p>
申请公布号 EP1918376(A1) 申请公布日期 2008.05.07
申请号 EP20060022946 申请日期 2006.11.03
申请人 MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V. 发明人
分类号 A61K31/713;A61K39/395;A61P35/00;C07K14/71;C07K16/28;C12N15/11;C12N15/113;C12Q1/68 主分类号 A61K31/713
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