发明名称 DERIVATIVE HAVING PPAR AGONISTIC ACTIVITY
摘要 A compound represented by the formula (I), a pharmaceutically acceptable salt thereof, or a solvate of the compound or salt: (I) wherein the ring Q represents a monocyclic aryl which may be substituted, a monocyclic heteroaryl which may be substituted, a fused aryl which may be substituted, a fused heteroaryl which may be substituted, or the like; Y1 represents a single bond,-NR6-or the like; the ring A represents a non-aromatic heterocyclic diyl which may be substituted; the formula:-Y2Z1-represents a group represented by the following formula: or ; R7 independently represents a hydrogen, a lower alkyl which may be substituted or the like; R8 and R9 independently represent a hydrogen or a lower alkyl which may be substituted; n is an integer of 0 to 3; Z1 represents a single bond, O, S or NR9; the ring B represents an aromatic carbocyclic diyl which may be substituted or an aromatic heterocyclic diyl which may be substituted; Y3 represents a single bond, a lower alkylene which may be substituted and may have-O-inserted therein, a lower alkenylene which may be substituted, or the like; and Z2 represents COOR3 or the like.
申请公布号 KR20080039946(A) 申请公布日期 2008.05.07
申请号 KR20087004732 申请日期 2008.02.27
申请人 SHIONOGI & CO., LTD.;INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. 发明人 ITAI AKIKO;MUTO SUSUMU;TOKUYAMA RYUKO;FUKASAWA HIROSHI;OHARA TAKAFUMI;KATO TERUKAZU
分类号 C07D277/82;A61K31/4439;A61P3/04;C07D417/14 主分类号 C07D277/82
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