| 发明名称 |
USE OF ANTIBODIES AGAINST THE MUC18 ANTIGEN |
| 摘要 |
<p>The present invention relates generally to the generation and characterization of anti-MUC18 monoclonal antibodies. The invention further relates to the use of such anti-MUC18 antibodies in the diagnosis and treatment of disorders associated with increased activity of MUC18, in particular, tumors, such as melanomas.</p> |
| 申请公布号 |
EP1467757(B1) |
申请公布日期 |
2008.05.07 |
| 申请号 |
EP20020797517 |
申请日期 |
2002.12.26 |
| 申请人 |
AMGEN FREMONT INC.;BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM |
发明人 |
BAR-ELI, MENASHE;GREEN, LARRY L. |
| 分类号 |
A61K39/395;A61K51/00;A61K47/48;A61K51/10;A61P35/00;A61P35/04;A61P43/00;C07K16/00;C07K16/18;C07K16/28;C07K16/30 |
主分类号 |
A61K39/395 |
| 代理机构 |
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